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Antidepressant induced liver injury can be irreversibleAntidepressant drugs can cause drug-induced liver injury (DILI). Although an infrequent event, antidepressant-induced liver injury can be irreversible! The research was conducted by a team of doctors from France. These doctors also concluded that Antidepressant liver toxicity has been underestimated and that liver damage can occur unrelated to dosage. Liver damage may occur between several days and 6 months after initiation of an antidepressant use. The study recommends Antidepressants "should be discontinued immediately" in any patient with suspected drug-induced liver injury. The researchers found, In some instances, life-threatening antidepressant-induced liver injury has been involved in liver failure or death. This study is just one of numerous recent studies that have found dangerous health side effects to Antidepressant medication use. Antidepressants have been found to (i) disrupt normal and healthy metabolism, (ii) have unhealthy nerve and muscular side effects, (iii) have unhealthy cardiovascular side effects, (iv) cause significant weight gain and (v) be a significant contributing factor causing Type 2 Diabetes. The antidepressants associated with greater risks of hepatotoxicity include iproniazid, nefazodone, phenelzine, imipramine, amitriptyline, duloxetine, bupropion, trazodone, tianeptine, and agomelatine. More about Ralph Teller. See Ralph's 1Vigor Log Calendar. <-- back to top |
Antipsychotics Articles Antidepressant-Induced Liver Injury: A Review for Clinicians, Cosmin Sebastian Voican, M.D., Ph.D., AP-HP Hôpital Bicêtre, Kremlin-Bicêtre, France, The American Journal of Psychiatry Antipsychotics Increase Risk of Type 2 Diabetes in Children and Young Adults, Alba Morales Pozzo, MD; Chief Editor: Stephen Kemp, MD, PhD, Medscape Implications of Marked Weight Gain Associated With Antipsychotic Medications in Children and Adolescents , Christopher K. Varley, MD and Jon McClellan, MD, JAMA Children and adolesents experience substantial antipsychotic medication caused weight gain and adverse metabolic effects, with more than half gaining more than 7% of their total body weight. Smoking and Mental Illness: Results From Population Surveys in Australia and the United States , David Lawrence; Francis Mitrou; Stephen R Zubrick, BMC Public Health Antidepressants Linked to Increased Risk for Death, Stroke in Postmenopausal Women , Pam Harrison, Department of Community Health Sciences, University of Calgary, Medscape Weight Gain in Relation to Major Depression and Antidepressant Medication Use , Patten SB, Medscape Medical News Antidepressants May Only Be Effective in Treatment of the Severest Depression , Caroline Cassels, Medscape Medical News Whole Diet May Ward Off Depression and Anxiety , Caroline Cassels, Medscape Medical News Unintentional Drug Poisoning (overdose) Deaths: A National Epidemic
, Bret Stetka, MD, Medscape Broad Review of FDA Trials Suggests Antidepressants Only Marginally Better than Placebo, Deborah Brauser, Medscape Antidepressant Use Linked with Increased Artherosclerosis Measured by Carotoid IMT, Heartwire, Medscape Mom's Antidepressant Use Linked to Autism Risk in Children, Psychiatry, Medscape More Evidence Confirms Diet's Link to Mental Health, Caroline Cassels, Psychiatry, Medscape Tricyclic Antidepressants Linked to Increased Cardiovascular Risk, Megan Brooks, Medscape |